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Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression

Although there is great interest in harnessing the immunosuppressive potential of FOXP3(+) regulatory T cells (Tregs) for treating autoimmunity, a sizeable knowledge gap exists regarding Treg fate in human disease. In juvenile idiopathic arthritis (JIA) patients, we have previously reported that aty...

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Detalles Bibliográficos
Autores principales:	Bending, David, Giannakopoulou, Eirini, Lom, Hannah, Wedderburn, Lucy R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Clinical and Human Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671090/ https://www.ncbi.nlm.nih.gov/pubmed/26561546 http://dx.doi.org/10.4049/jimmunol.1500391

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