Cargando…

The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis

The sensitivity and accuracy of the Risk/Injury/Failure/Loss/End-stage (RIFLE) versus acute kidney injury Network (AKIN) criteria for acute kidney injury (AKI) in critically ill patients remains uncertain. Therefore, we performed a systematic review and meta-analysis to investigate the incidence and...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Jiachuan, Tang, Xi, Hu, Zhangxue, Nie, Ling, Wang, Yiqin, Zhao, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671151/
https://www.ncbi.nlm.nih.gov/pubmed/26639440
http://dx.doi.org/10.1038/srep17917
_version_ 1782404360134721536
author Xiong, Jiachuan
Tang, Xi
Hu, Zhangxue
Nie, Ling
Wang, Yiqin
Zhao, Jinghong
author_facet Xiong, Jiachuan
Tang, Xi
Hu, Zhangxue
Nie, Ling
Wang, Yiqin
Zhao, Jinghong
author_sort Xiong, Jiachuan
collection PubMed
description The sensitivity and accuracy of the Risk/Injury/Failure/Loss/End-stage (RIFLE) versus acute kidney injury Network (AKIN) criteria for acute kidney injury (AKI) in critically ill patients remains uncertain. Therefore, we performed a systematic review and meta-analysis to investigate the incidence and prognostic value of the RIFLE versus AKIN criteria for AKI in critically ill patients. Literatures were identified by searching Medline, Embase, PubMed, and China National Knowledge Infrastructure (CNKI) database. Nineteen studies with 171,889 participants were included. The pooled estimates of relative risk (RR) were analyzed. We found that the RIFLE and AKIN criteria is different for the incidence of AKI in intensive care unit (ICU) patients (P = 0.02, RR = 0.88), while not for cardiac surgery patients (P = 0.30, RR = 0.93). For AKI-related hospital mortality, the AKIN criteria did not show a better ability in predicting hospital mortality in either ICU (P = 0.19, RR = 1.01) or cardiac surgery patients (P = 0.61, RR = 0.98) compared to RIFLE criteria. Our findings supported that the AKIN criteria can identify more patients in classifying AKI compared to RIFLE criteria, but not showing a better ability in predicting hospital mortality. Moreover, both RIFLE and AKIN criteria for AKI in cardiac surgery patients had better predictive ability compared with the ICU patients.
format Online
Article
Text
id pubmed-4671151
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-46711512015-12-11 The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis Xiong, Jiachuan Tang, Xi Hu, Zhangxue Nie, Ling Wang, Yiqin Zhao, Jinghong Sci Rep Article The sensitivity and accuracy of the Risk/Injury/Failure/Loss/End-stage (RIFLE) versus acute kidney injury Network (AKIN) criteria for acute kidney injury (AKI) in critically ill patients remains uncertain. Therefore, we performed a systematic review and meta-analysis to investigate the incidence and prognostic value of the RIFLE versus AKIN criteria for AKI in critically ill patients. Literatures were identified by searching Medline, Embase, PubMed, and China National Knowledge Infrastructure (CNKI) database. Nineteen studies with 171,889 participants were included. The pooled estimates of relative risk (RR) were analyzed. We found that the RIFLE and AKIN criteria is different for the incidence of AKI in intensive care unit (ICU) patients (P = 0.02, RR = 0.88), while not for cardiac surgery patients (P = 0.30, RR = 0.93). For AKI-related hospital mortality, the AKIN criteria did not show a better ability in predicting hospital mortality in either ICU (P = 0.19, RR = 1.01) or cardiac surgery patients (P = 0.61, RR = 0.98) compared to RIFLE criteria. Our findings supported that the AKIN criteria can identify more patients in classifying AKI compared to RIFLE criteria, but not showing a better ability in predicting hospital mortality. Moreover, both RIFLE and AKIN criteria for AKI in cardiac surgery patients had better predictive ability compared with the ICU patients. Nature Publishing Group 2015-12-07 /pmc/articles/PMC4671151/ /pubmed/26639440 http://dx.doi.org/10.1038/srep17917 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Xiong, Jiachuan
Tang, Xi
Hu, Zhangxue
Nie, Ling
Wang, Yiqin
Zhao, Jinghong
The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis
title The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis
title_full The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis
title_fullStr The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis
title_full_unstemmed The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis
title_short The RIFLE versus AKIN classification for incidence and mortality of acute kidney injury in critical ill patients: A meta-analysis
title_sort rifle versus akin classification for incidence and mortality of acute kidney injury in critical ill patients: a meta-analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671151/
https://www.ncbi.nlm.nih.gov/pubmed/26639440
http://dx.doi.org/10.1038/srep17917
work_keys_str_mv AT xiongjiachuan therifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT tangxi therifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT huzhangxue therifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT nieling therifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT wangyiqin therifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT zhaojinghong therifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT xiongjiachuan rifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT tangxi rifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT huzhangxue rifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT nieling rifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT wangyiqin rifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis
AT zhaojinghong rifleversusakinclassificationforincidenceandmortalityofacutekidneyinjuryincriticalillpatientsametaanalysis