Cargando…

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle

The malaria parasite Plasmodium falciparum replicates in an intraerythrocytic parasitophorous vacuole (PV). The most abundant P. falciparum PV protein, called SERA5, is essential in blood stages and possesses a papain-like domain, prompting speculation that it functions as a proteolytic enzyme. Unus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stallmach, Robert, Kavishwar, Manoli, Withers-Martinez, Chrislaine, Hackett, Fiona, Collins, Christine R, Howell, Steven A, Yeoh, Sharon, Knuepfer, Ellen, Atid, Avshalom J, Holder, Anthony A, Blackman, Michael J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671257/ https://www.ncbi.nlm.nih.gov/pubmed/25599609 http://dx.doi.org/10.1111/mmi.12941

Ejemplares similares

The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes
por: Collins, Christine R., et al.
Publicado: (2017)

An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery
por: Collins, Christine R., et al.
Publicado: (2009)

Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor
por: Tan, Michele S Y, et al.
Publicado: (2021)

Antibodies in malarial sera to parasite antigens in the membrane of erythrocytes infected with early asexual stages of Plasmodium falciparum
Publicado: (1984)

Essentiality of Plasmodium falciparum plasmepsin V
por: Boonyalai, Nonlawat, et al.
Publicado: (2018)

A multifunctional serine protease primes the malaria parasite for red blood cell invasion
por: Koussis, Konstantinos, et al.
Publicado: (2009)

Proteolytic Activation of the Essential Parasitophorous Vacuole Cysteine Protease SERA6 Accompanies Malaria Parasite Egress from Its Host Erythrocyte
por: Ruecker, Andrea, et al.
Publicado: (2012)

Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle
por: Collins, Christine R, et al.
Publicado: (2013)

Identification of a Plasmodium falciparum Phospholipid Transfer Protein
por: van Ooij, Christiaan, et al.
Publicado: (2013)

Juxtamembrane Shedding of Plasmodium falciparum AMA1 Is Sequence Independent and Essential, and Helps Evade Invasion-Inhibitory Antibodies
por: Olivieri, Anna, et al.
Publicado: (2011)

Correction: Juxtamembrane Shedding of Plasmodium falciparum AMA1 Is Sequence Independent and Essential, and Helps Evade Invasion-Inhibitory Antibodies
por: Olivieri, Anna, et al.
Publicado: (2012)

Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D
por: Zogota, Rimants, et al.
Publicado: (2019)

Roles of BrlA and AbaA in Mediating Asexual and Insect Pathogenic Lifecycles of Metarhizium robertsii
por: Zhang, Jin-Guan, et al.
Publicado: (2022)

Molecular Identification of a Malaria Merozoite Surface Sheddase
por: Harris, Philippa K, et al.
Publicado: (2005)

Cultivation of Asexual Intraerythrocytic Stages of Plasmodium falciparum
por: Basco, Leonardo K.
Publicado: (2023)

Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite
por: O'Donnell, Rebecca A., et al.
Publicado: (2006)

The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin
por: Withers-Martinez, Chrislaine, et al.
Publicado: (2014)

Corrigendum: The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin
por: Withers-Martinez, Chrislaine, et al.
Publicado: (2014)

PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs
por: van der Velden, Maarten, et al.
Publicado: (2015)

Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress
por: Collins, Christine R., et al.
Publicado: (2013)

Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function
por: Koussis, Konstantinos, et al.
Publicado: (2020)

Plasmodium falciparum in vitro continuous culture conditions: A comparison of parasite susceptibility and tolerance to anti-malarial drugs throughout the asexual intra-erythrocytic life cycle
por: Duffy, Sandra, et al.
Publicado: (2017)

The Motor Complex of Plasmodium falciparum: PHOSPHORYLATION BY A CALCIUM-DEPENDENT PROTEIN KINASE
por: Green, Judith L., et al.
Publicado: (2008)

Role of Melatonin in the Synchronization of Asexual Forms in the Parasite Plasmodium falciparum
por: Singh, Maneesh Kumar, et al.
Publicado: (2020)

Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass
por: Duffy, Michael F., et al.
Publicado: (2022)

Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1
por: Lidumniece, Elina, et al.
Publicado: (2021)

pH Feedback Lifecycles Programmed by Enzymatic Logic Gates Using Common Foods as Fuels
por: Fan, Xinlong, et al.
Publicado: (2021)

Transcription Sites Are Developmentally Regulated during the Asexual Cycle of Plasmodium falciparum
por: Moraes, Carolina B., et al.
Publicado: (2013)

Internalization of Erythrocyte Acylpeptide Hydrolase Is Required for Asexual Replication of Plasmodium falciparum
por: Elahi, Rubayet, et al.
Publicado: (2019)

Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum
por: Elahi, Rubayet, et al.
Publicado: (2019)

Reply to: Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass
por: Thomson-Luque, Richard, et al.
Publicado: (2022)

Molecular Determinants of Binding to the Plasmodium Subtilisin-like Protease 1
por: Fulle, Simone, et al.
Publicado: (2013)

The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake
por: Sherling, Emma S, et al.
Publicado: (2017)

Product lifecycle management
por: Stark, John
Publicado: (2016)

ITIL and the Information Lifecycle
por: AXELOS
Publicado: (2014)

The Lean Product Lifecycle
por: Viki, Tendayi
Publicado: (2018)

Product lifecycle management
por: Saaksvuori, Antti, et al.
Publicado: (2008)

The Molecular Cloud Lifecycle
por: Chevance, Mélanie, et al.
Publicado: (2020)

Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children
por: Sowunmi, Akintunde, et al.
Publicado: (2011)

The clinical and biochemical features of complicated falciparum malarial nephropathy
por: Rath, Debasmita, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_slfhuk9ofq8ssd42igv1lp59pl