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A Novel Method of Determining the Functional Effects of a Minor Genetic Modification of a Protein

Contraction of muscles results from the ATP-coupled cyclic interactions of the myosin cross-bridges with actin filaments. Macroscopic parameters of contraction, such as maximum tension, speed of shortening, or ATPase activity, are unlikely to reveal differences between the wild-type and mutated (MUT...

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Detalles Bibliográficos
Autores principales:	Nagwekar, Janhavi, Duggal, Divya, Midde, Krishna, Rich, Ryan, Liang, Jingsheng, Kazmierczak, Katarzyna, Huang, Wenrui, Fudala, Rafal, Gryczynski, Ignacy, Gryczynski, Zygmunt, Szczesna-Cordary, Danuta, Borejdo, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671333/ https://www.ncbi.nlm.nih.gov/pubmed/26664906 http://dx.doi.org/10.3389/fcvm.2015.00035

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