Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis

The non-receptor tyrosine phosphatase PTPN22 has a vital function in inhibiting antigen-receptor signaling in T cells, while polymorphisms in the PTPN22 gene are important risk alleles in human autoimmune diseases. We recently reported that a key physiological function of PTPN22 was to prevent naïve...

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Detalles Bibliográficos
Autores principales: Salmond, Robert J, Brownlie, Rebecca J, Zamoyska, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671365/
https://www.ncbi.nlm.nih.gov/pubmed/25715232
http://dx.doi.org/10.1080/15384101.2015.1007018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671365/
https://www.ncbi.nlm.nih.gov/pubmed/25715232
http://dx.doi.org/10.1080/15384101.2015.1007018

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