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Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins
Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H(2)O(2)), react with thiolates to form oxidative post-translational modifications, enabling physiological redox signaling. Cardiac disease and aging are associated with oxidative stress wh...
Autores principales: | Yao, Chunxiang, Behring, Jessica B., Shao, Di, Sverdlov, Aaron L., Whelan, Stephen A., Elezaby, Aly, Yin, Xiaoyan, Siwik, Deborah A., Seta, Francesca, Costello, Catherine E., Cohen, Richard A., Matsui, Reiko, Colucci, Wilson S., McComb, Mark E., Bachschmid, Markus M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671598/ https://www.ncbi.nlm.nih.gov/pubmed/26642319 http://dx.doi.org/10.1371/journal.pone.0144025 |
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