Cargando…
MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer Cells
The p53 tumor suppressor protein plays a critical role in cellular stress and cancer prevention. A number of post-transcriptional regulators, termed microRNAs, are closely connected with the p53-mediated cellular networks. While the molecular interactions among p53 and microRNAs have emerged, a syst...
Autores principales: | Moore, Richard, Ooi, Hsu Kiang, Kang, Taek, Bleris, Leonidas, Ma, Lan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671655/ https://www.ncbi.nlm.nih.gov/pubmed/26642352 http://dx.doi.org/10.1371/journal.pcbi.1004653 |
Ejemplares similares
-
IL-17/miR-192/IL-17Rs Regulatory Feedback Loop Facilitates Multiple Myeloma Progression
por: Sun, Yuanyuan, et al.
Publicado: (2014) -
Coordination of miR-192 and miR-22 in p53-Mediated Cell Fate Decision
por: Sun, Cheng-Yuan, et al.
Publicado: (2019) -
Positive Feedback Promotes Oscillations in Negative Feedback Loops
por: Ananthasubramaniam, Bharath, et al.
Publicado: (2014) -
Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation
por: Kang, Taek, et al.
Publicado: (2020) -
Loss of miR-192-5p initiates a hyperglycolysis and stemness positive feedback in hepatocellular carcinoma
por: Gu, Yuanzhuo, et al.
Publicado: (2020)