Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes

Leishmaniasis, a human parasitic disease with manifestations ranging from cutaneous ulcerations to fatal visceral infection, is caused by several Leishmania species. These protozoan parasites replicate as extracellular, flagellated promastigotes in the gut of a sandfly vector and as amastigotes insi...

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Detalles Bibliográficos
Autores principales: de Paiva, Rita Marcia Cardoso, Grazielle-Silva, Viviane, Cardoso, Mariana Santos, Nakagaki, Brenda Naemi, Mendonça-Neto, Rondon Pessoa, Canavaci, Adriana Monte Cassiano, Souza Melo, Normanda, Martinelli, Patrícia Massara, Fernandes, Ana Paula, daRocha, Wanderson Duarte, Teixeira, Santuza M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671664/
https://www.ncbi.nlm.nih.gov/pubmed/26641088
http://dx.doi.org/10.1371/journal.ppat.1005296

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