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Correlated Evolution of Nucleotide Positions within Splice Sites in Mammals
Splice sites (SSs)—short nucleotide sequences flanking introns—are under selection for spliceosome binding, and adhere to consensus sequences. However, non-consensus nucleotides, many of which probably reduce SS performance, are frequent. Little is known about the mechanisms maintaining such apparen...
Autores principales: | Denisov, Stepan, Bazykin, Georgii, Favorov, Alexander, Mironov, Andrey, Gelfand, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671708/ https://www.ncbi.nlm.nih.gov/pubmed/26642327 http://dx.doi.org/10.1371/journal.pone.0144388 |
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