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Kicking against the PRCs – A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2
The Polycomb group (PcG) and trithorax group (trxG) genes play crucial roles in development by regulating expression of homeotic and other genes controlling cell fate. Both groups catalyse modifications of chromatin, particularly histone methylation, leading to epigenetic changes that affect gene ac...
Autores principales: | Liang, Shih Chieh, Hartwig, Ben, Perera, Pumi, Mora-García, Santiago, de Leau, Erica, Thornton, Harry, de Alves, Flavia Lima, Rapsilber, Juri, Yang, Suxin, James, Geo Velikkakam, Schneeberger, Korbinian, Finnegan, E. Jean, Turck, Franziska, Goodrich, Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671723/ https://www.ncbi.nlm.nih.gov/pubmed/26642436 http://dx.doi.org/10.1371/journal.pgen.1005660 |
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