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The relationship between UGT1A1 gene polymorphism and irinotecan effect on extensive-stage small-cell lung cancer
AIMS: To analyze the distribution of uridine diphosphate glucuronosyltransferase (UGT)1A1 gene polymorphisms in Chinese patients with extensive-stage small-cell lung cancer (E-SCLC), and to evaluate correlations between the UGT1A1 gene polymorphisms and toxicity, and efficacy of irinotecan (CPT-11)...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671801/ https://www.ncbi.nlm.nih.gov/pubmed/26664141 http://dx.doi.org/10.2147/OTT.S95149 |