Cargando…

Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J(2) on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis

OBJECTIVE: 15-Deoxy-Δ12,14-prostaglandin J(2) (15d-PGJ(2)) induces reactive oxygen species (ROS)-mediated apoptosis in many malignant cells, which has not been studied in hepatoma cells. In this study, we investigated whether 15d-PGJ(2) induced apoptosis in hepatocellular carcinoma (HCC) associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Kan, Dai, Weiqi, Wang, Fan, Xia, Yujing, Li, Jingjing, Li, Sainan, Liu, Tong, Zhang, Rong, Wang, Jianrong, Lu, Wenxia, Zhou, Yuqing, Yin, Qin, Zheng, Yuanyuan, Abudumijiti, Huerxidan, Chen, Rongxia, Lu, Jie, Zhou, Yingqun, Guo, Chuanyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671813/ https://www.ncbi.nlm.nih.gov/pubmed/26664142 http://dx.doi.org/10.2147/OTT.S92832

Ejemplares similares

Astaxanthin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells via Inhibition of Nf-Κb P65 and Wnt/Β-Catenin in Vitro
por: Li, Jingjing, et al.
Publicado: (2015)

Systematic review and meta-analysis: bezafibrate in patients with primary biliary cirrhosis
por: Yin, Qin, et al.
Publicado: (2015)

Combination therapy of ursodeoxycholic acid and budesonide for PBC–AIH overlap syndrome: a meta-analysis
por: Zhang, Huawei, et al.
Publicado: (2015)

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice
por: Dai, Weiqi, et al.
Publicado: (2015)

Protective Effects of Astaxanthin on ConA-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis
por: Li, Jingjing, et al.
Publicado: (2015)

Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice
por: Li, Jingjing, et al.
Publicado: (2015)

15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity
por: Chen, Kan, et al.
Publicado: (2014)

Erratum to “15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity”
por: Chen, Kan, et al.
Publicado: (2014)

The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice
por: Zhou, Yingqun, et al.
Publicado: (2015)

Effects of Omega-3 Fatty Acid in Nonalcoholic Fatty Liver Disease: A Meta-Analysis
por: Lu, Wenxia, et al.
Publicado: (2016)

Combination therapy of fenofibrate and ursodeoxycholic acid in patients with primary biliary cirrhosis who respond incompletely to UDCA monotherapy: a meta-analysis
por: Zhang, Yan, et al.
Publicado: (2015)

Oncogenic role of the Notch pathway in primary liver cancer (Review)
por: Lu, Jie, et al.
Publicado: (2016)

Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3
por: Li, Sainan, et al.
Publicado: (2016)

Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis
por: Li, Jingjing, et al.
Publicado: (2016)

15-deoxy-Δ(12,14)-prostaglandin J(2) in neurodegenerative diseases and cancers
por: Yagami, Tatsurou, et al.
Publicado: (2017)

15-Deoxy-∆-(12,14)-Prostaglandin J2 (15d-PGJ2), an Endogenous Ligand of PPAR-γ: Function and Mechanism
por: Li, Jingjing, et al.
Publicado: (2019)

Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3
por: Xu, Ling, et al.
Publicado: (2016)

Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway
por: Liu, Tong, et al.
Publicado: (2016)

Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy
por: Li, Jingjing, et al.
Publicado: (2016)

Rac1 modification by an electrophilic 15-deoxy Δ(12,14)-prostaglandin J(2) analog
por: Wall, S.B., et al.
Publicado: (2015)

Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in mice
por: Li, Jingjing, et al.
Publicado: (2017)

In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity
por: Li, Sainan, et al.
Publicado: (2016)

Feedback Control of the Arachidonate Cascade in Osteoblastic Cells by 15-deoxy-Δ(12,14)-Prostaglandin J(2)
por: Ishino, Hidetaka, et al.
Publicado: (2008)

Proteomic Identification of Protein Targets for 15-Deoxy-Δ(12,14)-Prostaglandin J(2) in Neuronal Plasma Membrane
por: Yamamoto, Yasuhiro, et al.
Publicado: (2011)

15-Deoxy-Δ(12,14)-Prostaglandin J(2) Inhibits Macrophage Colonization by Salmonella enterica Serovar Typhimurium
por: Buckner, Michelle M. C., et al.
Publicado: (2013)

Protective Effects of N-Acetylcysteine in Concanavalin A-Induced Hepatitis in Mice
por: Wang, Chengfen, et al.
Publicado: (2015)

Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway
por: Wu, Liwei, et al.
Publicado: (2017)

Effects of 15-Deoxy-Δ(12,14)-Prostaglandin J2 (15d-PGJ2) and Rosiglitazone on Human Vδ2(+) T Cells
por: Li, Haishan, et al.
Publicado: (2009)

15-Deoxy-Δ(12,14) Prostaglandin J(2) Reduces the Formation of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice
por: Seno, Takahiro, et al.
Publicado: (2011)

Correction: Proteomic Identification of Protein Targets for 15-Deoxy-Δ(12,14)-Prostaglandin J(2) in Neuronal Plasma Membrane
por: Yamamoto, Yasuhiro, et al.
Publicado: (2011)

Changes in the Th1 : Th2 Cytokine Bias in Pregnancy and the Effects of the Anti-Inflammatory Cyclopentenone Prostaglandin 15-Deoxy-Δ(12,14)-Prostaglandin J(2)
por: Sykes, Lynne, et al.
Publicado: (2012)

15-Deoxy-Δ(12,14)-prostaglandin J(2) Induces Apoptosis and Upregulates SOCS3 in Human Thyroid Cancer Cells
por: Trindade-da-Silva, Carlos Antônio, et al.
Publicado: (2016)

15-Deoxy-Δ(12,14)-Prostaglandin J(2) Modifies Components of the Proteasome and Inhibits Inflammatory Responses in Human Endothelial Cells
por: Marcone, Simone, et al.
Publicado: (2016)

The Effects of Co-Treatment of 9-cis-Retinoic Acid and 15-Deoxy-Δ (12,14)-prostaglandin J2 on Microglial Activation
por: Hsu, Pei-Chien, et al.
Publicado: (2011)

Cytotoxic effects of 15-deoxy-Δ12,14-prostaglandin J2 alone and in combination with dasatinib against uterine sarcoma in vitro
por: Kawakita, Takako, et al.
Publicado: (2017)

Synergistic effects of 15-deoxy Δ(12,14)-prostaglandin J(2) on the anti-tumor activity of doxorubicin in renal cell carcinoma
por: Yamamoto, Yasuhiro, et al.
Publicado: (2016)

15-deoxy-Δ(12, 14)-prostaglandin J(2) enhances anticancer activities independently of VHL status in renal cell carcinomas
por: Koma, Hiromi, et al.
Publicado: (2019)

A meta-analysis of ursodeoxycholic acid therapy versus combination therapy with corticosteroids for PBC-AIH-overlap syndrome: evidence from 97 monotherapy and 117 combinations
por: Zhang, Huawei, et al.
Publicado: (2015)

The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling
por: Yu, Qiang, et al.
Publicado: (2018)

15-Deoxy-Δ(12,14)-prostaglandin J(2) inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction
por: Wu, Ya-Chieh, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pgd6d1q5nug61dons9b9eanv78