A metastatic colon adenocarcinoma harboring BRAF V600E has a durable major response to dabrafenib/trametinib and chemotherapy

The subset of metastatic colorectal adenocarcinomas that harbor BRAF V600E mutations are aggressive tumors with significantly shortened survival and limited treatment options. Here we present a colorectal cancer patient whose disease progressed through standard chemotherapy and who developed liver m...

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Detalles Bibliográficos
Autores principales: Williams, Casey B, McMahon, Caitlin, Ali, Siraj M, Abramovitz, Mark, Williams, Kirstin A, Klein, Jessica, McKean, Heidi, Yelensky, Roman, George, Thomas J, Elvin, Julia A, Soman, Salil, Lipson, Doron, Chmielecki, Juliann, Morosini, Deborah, Miller, Vincent A, Stephens, Philip J, Ross, Jeffrey S, Leyland-Jones, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671814/
https://www.ncbi.nlm.nih.gov/pubmed/26664139
http://dx.doi.org/10.2147/OTT.S90766

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