Inhibition of mTOR Pathway by Rapamycin Reduces Brain Damage in Rats Subjected to Transient Forebrain Ischemia

The aims of this study are to clarify the role of mTOR in mediating cerebral ischemic brain damage and the effects of rapamycin on ischemic outcomes. Ten minutes of forebrain ischemia was induced in rats, and their brains were sampled after 3 h, 16 h, and 7 days reperfusion for histology, immunohist...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Hei, Changhun, Liu, Ping, Song, Yaozu, Thomas, Taylor, Tshimanga, Sylvie, Wang, Feng, Niu, Jianguo, Sun, Tao, Li, P. Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672000/
https://www.ncbi.nlm.nih.gov/pubmed/26681922
http://dx.doi.org/10.7150/ijbs.12930

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