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The Role of Stefin B in Neuro-inflammation
Stefin B (cystatin B) is an endogenous cysteine cathepsin inhibitor localized in the cytosol, mitochondria and nucleus. Its expression is upregulated upon macrophage activation and cellular stress. Mutations in the gene of stefin B are associated with the neurodegenerative disease known as Unverrich...
Autor principal: | Kopitar-Jerala, Nataša |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672043/ https://www.ncbi.nlm.nih.gov/pubmed/26696823 http://dx.doi.org/10.3389/fncel.2015.00458 |
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