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Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test
BACKGROUND: Pulmonary vein isolation (PVI) has become an important option for treating patients with atrial fibrillation (AF). Periesophageal nerve (PEN) injury after PVI causes pyloric spasms and gastric hypomotility. This study aimed to clarify the impact of PVI on gastric motility and assess the...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672080/ https://www.ncbi.nlm.nih.gov/pubmed/26702316 http://dx.doi.org/10.1016/j.joa.2015.06.004 |
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author | Kanaeda, Tomonori Ueda, Marehiko Arai, Makoto Ishimura, Masayuki Kajiyama, Takatsugu Hashiguchi, Naotaka Nakano, Masahiro Kondo, Yusuke Hiranuma, Yasunori Oyamada, Arata Yokosuka, Osamu Kobayashi, Yoshio |
author_facet | Kanaeda, Tomonori Ueda, Marehiko Arai, Makoto Ishimura, Masayuki Kajiyama, Takatsugu Hashiguchi, Naotaka Nakano, Masahiro Kondo, Yusuke Hiranuma, Yasunori Oyamada, Arata Yokosuka, Osamu Kobayashi, Yoshio |
author_sort | Kanaeda, Tomonori |
collection | PubMed |
description | BACKGROUND: Pulmonary vein isolation (PVI) has become an important option for treating patients with atrial fibrillation (AF). Periesophageal nerve (PEN) injury after PVI causes pyloric spasms and gastric hypomotility. This study aimed to clarify the impact of PVI on gastric motility and assess the prevalence of gastric hypomotility after PVI. METHODS: Thirty consecutive patients with AF underwent PVI under luminal esophageal temperature (LET) monitoring. The (13)C-acetate breath test was conducted before and after the procedure for all patients (PVI group). Gastric emptying was evaluated using the time to peak concentration of (13)CO(2) (T(max)). This test was also conducted in another 20 patients who underwent catheter ablation procedures other than PVI (control group). RESULTS: The number of patients with abnormal T(max) (≥75 min) increased from seven (23%) to 13 (43%) and from three (15%) to five (25%) after the procedure in the PVI group and control group, respectively. The mean T(max) was longer after PVI than before PVI (64±14 min vs. 57±15 min, p=0.006), whereas there was no significant difference before and after the procedure in the control group. However, no significant difference in ΔT(max) was observed between the two groups (p=0.27). No patients suffered from symptomatic gastric hypomotility. CONCLUSIONS: Asymptomatic gastric hypomotility occurred more often after PVI. However, the average impact of PVI on gastric motility was minimal. |
format | Online Article Text |
id | pubmed-4672080 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-46720802015-12-23 Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test Kanaeda, Tomonori Ueda, Marehiko Arai, Makoto Ishimura, Masayuki Kajiyama, Takatsugu Hashiguchi, Naotaka Nakano, Masahiro Kondo, Yusuke Hiranuma, Yasunori Oyamada, Arata Yokosuka, Osamu Kobayashi, Yoshio J Arrhythm Original Article BACKGROUND: Pulmonary vein isolation (PVI) has become an important option for treating patients with atrial fibrillation (AF). Periesophageal nerve (PEN) injury after PVI causes pyloric spasms and gastric hypomotility. This study aimed to clarify the impact of PVI on gastric motility and assess the prevalence of gastric hypomotility after PVI. METHODS: Thirty consecutive patients with AF underwent PVI under luminal esophageal temperature (LET) monitoring. The (13)C-acetate breath test was conducted before and after the procedure for all patients (PVI group). Gastric emptying was evaluated using the time to peak concentration of (13)CO(2) (T(max)). This test was also conducted in another 20 patients who underwent catheter ablation procedures other than PVI (control group). RESULTS: The number of patients with abnormal T(max) (≥75 min) increased from seven (23%) to 13 (43%) and from three (15%) to five (25%) after the procedure in the PVI group and control group, respectively. The mean T(max) was longer after PVI than before PVI (64±14 min vs. 57±15 min, p=0.006), whereas there was no significant difference before and after the procedure in the control group. However, no significant difference in ΔT(max) was observed between the two groups (p=0.27). No patients suffered from symptomatic gastric hypomotility. CONCLUSIONS: Asymptomatic gastric hypomotility occurred more often after PVI. However, the average impact of PVI on gastric motility was minimal. Elsevier 2015-12 2015-07-14 /pmc/articles/PMC4672080/ /pubmed/26702316 http://dx.doi.org/10.1016/j.joa.2015.06.004 Text en © 2015 Japanese Heart Rhythm Society. Published by Elsevier B.V. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Kanaeda, Tomonori Ueda, Marehiko Arai, Makoto Ishimura, Masayuki Kajiyama, Takatsugu Hashiguchi, Naotaka Nakano, Masahiro Kondo, Yusuke Hiranuma, Yasunori Oyamada, Arata Yokosuka, Osamu Kobayashi, Yoshio Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test |
title | Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test |
title_full | Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test |
title_fullStr | Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test |
title_full_unstemmed | Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test |
title_short | Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test |
title_sort | evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)c-acetate breath test |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672080/ https://www.ncbi.nlm.nih.gov/pubmed/26702316 http://dx.doi.org/10.1016/j.joa.2015.06.004 |
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