Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity

The poor efficacy of the in vivo anti-tumor immune response has been partially attributed to ineffective T-cell responses mounted against the tumor. Fas-FasL-dependent activation-induced cell death (AICD) of T cells is believed to be a major contributor to compromised anti-tumor immunity. The molecu...

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Detalles Bibliográficos
Autores principales: Cao, K, Wang, G, Li, W, Zhang, L, Wang, R, Huang, Y, Du, L, Jiang, J, Wu, C, He, X, Roberts, A I, Li, F, Rabson, A B, Wang, Y, Shi, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672172/
https://www.ncbi.nlm.nih.gov/pubmed/25745993
http://dx.doi.org/10.1038/onc.2015.46

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