Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications?

The derivation of canine embryonic stem cells and generation of canine-induced pluripotent stem cells are significant achievements that have unlocked the potential for developing novel cell-based disease models, drug discovery platforms, and transplantation therapies in the dog. A progression from c...

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Detalles Bibliográficos
Autores principales: Betts, Dean H., Tobias, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672225/
https://www.ncbi.nlm.nih.gov/pubmed/26664969
http://dx.doi.org/10.3389/fvets.2015.00041
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author Betts, Dean H.
Tobias, Ian C.
author_facet Betts, Dean H.
Tobias, Ian C.
author_sort Betts, Dean H.
collection PubMed
description The derivation of canine embryonic stem cells and generation of canine-induced pluripotent stem cells are significant achievements that have unlocked the potential for developing novel cell-based disease models, drug discovery platforms, and transplantation therapies in the dog. A progression from concept to cure in this clinically relevant companion animal will not only help our canine patients but also help advance human regenerative medicine. Nevertheless, many issues remain to be resolved before pluripotent cells can be used clinically in a safe and reproducible manner.
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spelling pubmed-46722252015-12-10 Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications? Betts, Dean H. Tobias, Ian C. Front Vet Sci Veterinary Science The derivation of canine embryonic stem cells and generation of canine-induced pluripotent stem cells are significant achievements that have unlocked the potential for developing novel cell-based disease models, drug discovery platforms, and transplantation therapies in the dog. A progression from concept to cure in this clinically relevant companion animal will not only help our canine patients but also help advance human regenerative medicine. Nevertheless, many issues remain to be resolved before pluripotent cells can be used clinically in a safe and reproducible manner. Frontiers Media S.A. 2015-10-07 /pmc/articles/PMC4672225/ /pubmed/26664969 http://dx.doi.org/10.3389/fvets.2015.00041 Text en Copyright © 2015 Betts and Tobias. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Betts, Dean H.
Tobias, Ian C.
Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications?
title Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications?
title_full Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications?
title_fullStr Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications?
title_full_unstemmed Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications?
title_short Canine Pluripotent Stem Cells: Are They Ready for Clinical Applications?
title_sort canine pluripotent stem cells: are they ready for clinical applications?
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672225/
https://www.ncbi.nlm.nih.gov/pubmed/26664969
http://dx.doi.org/10.3389/fvets.2015.00041
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