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Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health
Immunometabolism is a relatively new research perspective, focusing on both metabolism and immunology and the cross-talk between these biological processes. Immunometabolism can be considered from two perspectives; 1) the role that immune cells play in organ metabolism and metabolic disease, and 2)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672240/ https://www.ncbi.nlm.nih.gov/pubmed/26664971 http://dx.doi.org/10.3389/fvets.2015.00044 |
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author | Arsenault, Ryan J. Kogut, Michael H. |
author_facet | Arsenault, Ryan J. Kogut, Michael H. |
author_sort | Arsenault, Ryan J. |
collection | PubMed |
description | Immunometabolism is a relatively new research perspective, focusing on both metabolism and immunology and the cross-talk between these biological processes. Immunometabolism can be considered from two perspectives; 1) the role that immune cells play in organ metabolism and metabolic disease, and 2) the metabolic processes that occur within immune cells and how they affect overall immunity. The gut may be the prototypical organ of immunometabolism. The gut is the site of nutrient absorption and is a major, if not the major, immune organ. We also describe the integration of kinomics and the species-specific peptide array to the study of the gut. This unique immunometabolic tool combined with the unique immunometabolic nature of the gut provides significant research potential to many animal health applications. |
format | Online Article Text |
id | pubmed-4672240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-46722402015-12-10 Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health Arsenault, Ryan J. Kogut, Michael H. Front Vet Sci Veterinary Science Immunometabolism is a relatively new research perspective, focusing on both metabolism and immunology and the cross-talk between these biological processes. Immunometabolism can be considered from two perspectives; 1) the role that immune cells play in organ metabolism and metabolic disease, and 2) the metabolic processes that occur within immune cells and how they affect overall immunity. The gut may be the prototypical organ of immunometabolism. The gut is the site of nutrient absorption and is a major, if not the major, immune organ. We also describe the integration of kinomics and the species-specific peptide array to the study of the gut. This unique immunometabolic tool combined with the unique immunometabolic nature of the gut provides significant research potential to many animal health applications. Frontiers Media S.A. 2015-10-13 /pmc/articles/PMC4672240/ /pubmed/26664971 http://dx.doi.org/10.3389/fvets.2015.00044 Text en Copyright © 2015 Arsenault and Kogut. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Arsenault, Ryan J. Kogut, Michael H. Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health |
title | Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health |
title_full | Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health |
title_fullStr | Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health |
title_full_unstemmed | Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health |
title_short | Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health |
title_sort | immunometabolism and the kinome peptide array: a new perspective and tool for the study of gut health |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672240/ https://www.ncbi.nlm.nih.gov/pubmed/26664971 http://dx.doi.org/10.3389/fvets.2015.00044 |
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