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Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications

Solid-state membranes are finding use in many applications in nanoelectronics and nanomedicine, from single molecule sensors to water filtration, and yet many of their electronics applications are limited by the relatively high current noise and low bandwidth stemming from the relatively high capaci...

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Detalles Bibliográficos
Autores principales: Balan, Adrian, Chien, Chen-Chi, Engelke, Rebecca, Drndić, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672352/
https://www.ncbi.nlm.nih.gov/pubmed/26644307
http://dx.doi.org/10.1038/srep17775
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author Balan, Adrian
Chien, Chen-Chi
Engelke, Rebecca
Drndić, Marija
author_facet Balan, Adrian
Chien, Chen-Chi
Engelke, Rebecca
Drndić, Marija
author_sort Balan, Adrian
collection PubMed
description Solid-state membranes are finding use in many applications in nanoelectronics and nanomedicine, from single molecule sensors to water filtration, and yet many of their electronics applications are limited by the relatively high current noise and low bandwidth stemming from the relatively high capacitance (>10 pF) of the membrane chips. To address this problem, we devised an integrated fabrication process to grow and define circular silicon nitride membranes on glass chips that successfully lower the chip capacitance to below 1 pF. We use these devices to demonstrate low-noise, high-bandwidth DNA translocation measurements. We also make use of this versatile, low-capacitance platform to suspend other thin, two-dimensional membrane such as graphene.
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spelling pubmed-46723522015-12-11 Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications Balan, Adrian Chien, Chen-Chi Engelke, Rebecca Drndić, Marija Sci Rep Article Solid-state membranes are finding use in many applications in nanoelectronics and nanomedicine, from single molecule sensors to water filtration, and yet many of their electronics applications are limited by the relatively high current noise and low bandwidth stemming from the relatively high capacitance (>10 pF) of the membrane chips. To address this problem, we devised an integrated fabrication process to grow and define circular silicon nitride membranes on glass chips that successfully lower the chip capacitance to below 1 pF. We use these devices to demonstrate low-noise, high-bandwidth DNA translocation measurements. We also make use of this versatile, low-capacitance platform to suspend other thin, two-dimensional membrane such as graphene. Nature Publishing Group 2015-12-08 /pmc/articles/PMC4672352/ /pubmed/26644307 http://dx.doi.org/10.1038/srep17775 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Balan, Adrian
Chien, Chen-Chi
Engelke, Rebecca
Drndić, Marija
Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications
title Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications
title_full Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications
title_fullStr Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications
title_full_unstemmed Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications
title_short Suspended Solid-state Membranes on Glass Chips with Sub 1-pF Capacitance for Biomolecule Sensing Applications
title_sort suspended solid-state membranes on glass chips with sub 1-pf capacitance for biomolecule sensing applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672352/
https://www.ncbi.nlm.nih.gov/pubmed/26644307
http://dx.doi.org/10.1038/srep17775
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