Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with...

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Detalles Bibliográficos
Autores principales: Park, Wan Beom, Perera, Ranawaka A.P.M., Choe, Pyoeng Gyun, Lau, Eric H.Y., Choi, Seong Jin, Chun, June Young, Oh, Hong Sang, Song, Kyoung-Ho, Bang, Ji Hwan, Kim, Eu Suk, Kim, Hong Bin, Park, Sang Won, Kim, Nam Joong, Man Poon, Leo Lit, Peiris, Malik, Oh, Myoung-don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672454/
https://www.ncbi.nlm.nih.gov/pubmed/26583829
http://dx.doi.org/10.3201/eid2112.151421
Descripción
Sumario:We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease.

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