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Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with...

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Autores principales: Park, Wan Beom, Perera, Ranawaka A.P.M., Choe, Pyoeng Gyun, Lau, Eric H.Y., Choi, Seong Jin, Chun, June Young, Oh, Hong Sang, Song, Kyoung-Ho, Bang, Ji Hwan, Kim, Eu Suk, Kim, Hong Bin, Park, Sang Won, Kim, Nam Joong, Man Poon, Leo Lit, Peiris, Malik, Oh, Myoung-don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672454/
https://www.ncbi.nlm.nih.gov/pubmed/26583829
http://dx.doi.org/10.3201/eid2112.151421
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author Park, Wan Beom
Perera, Ranawaka A.P.M.
Choe, Pyoeng Gyun
Lau, Eric H.Y.
Choi, Seong Jin
Chun, June Young
Oh, Hong Sang
Song, Kyoung-Ho
Bang, Ji Hwan
Kim, Eu Suk
Kim, Hong Bin
Park, Sang Won
Kim, Nam Joong
Man Poon, Leo Lit
Peiris, Malik
Oh, Myoung-don
author_facet Park, Wan Beom
Perera, Ranawaka A.P.M.
Choe, Pyoeng Gyun
Lau, Eric H.Y.
Choi, Seong Jin
Chun, June Young
Oh, Hong Sang
Song, Kyoung-Ho
Bang, Ji Hwan
Kim, Eu Suk
Kim, Hong Bin
Park, Sang Won
Kim, Nam Joong
Man Poon, Leo Lit
Peiris, Malik
Oh, Myoung-don
author_sort Park, Wan Beom
collection PubMed
description We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease.
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spelling pubmed-46724542015-12-08 Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea Park, Wan Beom Perera, Ranawaka A.P.M. Choe, Pyoeng Gyun Lau, Eric H.Y. Choi, Seong Jin Chun, June Young Oh, Hong Sang Song, Kyoung-Ho Bang, Ji Hwan Kim, Eu Suk Kim, Hong Bin Park, Sang Won Kim, Nam Joong Man Poon, Leo Lit Peiris, Malik Oh, Myoung-don Emerg Infect Dis Dispatch We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease. Centers for Disease Control and Prevention 2015-12 /pmc/articles/PMC4672454/ /pubmed/26583829 http://dx.doi.org/10.3201/eid2112.151421 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Park, Wan Beom
Perera, Ranawaka A.P.M.
Choe, Pyoeng Gyun
Lau, Eric H.Y.
Choi, Seong Jin
Chun, June Young
Oh, Hong Sang
Song, Kyoung-Ho
Bang, Ji Hwan
Kim, Eu Suk
Kim, Hong Bin
Park, Sang Won
Kim, Nam Joong
Man Poon, Leo Lit
Peiris, Malik
Oh, Myoung-don
Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
title Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
title_full Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
title_fullStr Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
title_full_unstemmed Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
title_short Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
title_sort kinetics of serologic responses to mers coronavirus infection in humans, south korea
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672454/
https://www.ncbi.nlm.nih.gov/pubmed/26583829
http://dx.doi.org/10.3201/eid2112.151421
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