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Choice of reference-guided sequence assembler and SNP caller for analysis of Listeria monocytogenes short-read sequence data greatly influences rates of error

BACKGROUND: The influences that different programs and conditions have on error rates of single-nucleotide polymorphism (SNP) analyses are poorly understood. Using Illumina short-read sequence data generated from Listeria monocytogenes strain HPB5622, we assessed the performance of four SNP callers...

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Detalles Bibliográficos
Autores principales: Pightling, Arthur W., Petronella, Nicholas, Pagotto, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672502/
https://www.ncbi.nlm.nih.gov/pubmed/26643440
http://dx.doi.org/10.1186/s13104-015-1689-4