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A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators

BACKGROUND: Wnt/β-catenin signaling is often portrayed as a simple pathway that is initiated by Wnt ligand at the cell surface leading, via linear series of interactions between ‘core pathway’ members, to the induction of nuclear transcription from genes flanked by β-catenin/TCF transcription factor...

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Detalles Bibliográficos
Autores principales: Freeman, Jamie, Smith, David, Latinkic, Branko, Ewan, Ken, Samuel, Lee, Zollo, Massimo, Marino, Natascia, Tyas, Lorraine, Jones, Nick, Dale, Trevor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672529/
https://www.ncbi.nlm.nih.gov/pubmed/26643252
http://dx.doi.org/10.1186/s12943-015-0475-1