Cargando…

A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators

BACKGROUND: Wnt/β-catenin signaling is often portrayed as a simple pathway that is initiated by Wnt ligand at the cell surface leading, via linear series of interactions between ‘core pathway’ members, to the induction of nuclear transcription from genes flanked by β-catenin/TCF transcription factor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Freeman, Jamie, Smith, David, Latinkic, Branko, Ewan, Ken, Samuel, Lee, Zollo, Massimo, Marino, Natascia, Tyas, Lorraine, Jones, Nick, Dale, Trevor C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672529/ https://www.ncbi.nlm.nih.gov/pubmed/26643252 http://dx.doi.org/10.1186/s12943-015-0475-1

Ejemplares similares

Early Activation of FGF and Nodal Pathways Mediates Cardiac Specification Independently of Wnt/β-Catenin Signaling
por: Samuel, Lee J., et al.
Publicado: (2009)

Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation
por: Haworth, Kim, et al.
Publicado: (2019)

Investigating h-Prune activation of Wnt signalling in breast cancer
por: Freeman, J, et al.
Publicado: (2008)

Dazap2 modulates transcription driven by the Wnt effector TCF-4
por: Lukas, Jan, et al.
Publicado: (2009)

Wnt target enhancer regulation by a CDX/TCF transcription factor collective and a novel DNA motif
por: Ramakrishnan, Aravinda-Bharathi, et al.
Publicado: (2021)

Ventricular cell fate can be specified until the onset of myocardial differentiation
por: Caporilli, Simona, et al.
Publicado: (2016)

Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation
por: Young, Rodrigo M, et al.
Publicado: (2019)

SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer
por: Ramakrishnan, Aravinda-Bharathi, et al.
Publicado: (2022)

Genetic Variants of Wnt Transcription Factor TCF-4 (TCF7L2) Putative Promoter Region Are Associated with Small Intestinal Crohn's Disease
por: Koslowski, Maureen J., et al.
Publicado: (2009)

Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells
por: Hrckulak, Dusan, et al.
Publicado: (2018)

Structure-Function Analysis of the C-clamp of TCF/Pangolin in Wnt/ß-catenin Signaling
por: Ravindranath, Aditi, et al.
Publicado: (2014)

VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
por: Zhang, Haifeng, et al.
Publicado: (2021)

Wnt-Mediated Repression via Bipartite DNA Recognition by TCF in the Drosophila Hematopoietic System
por: Zhang, Chen U., et al.
Publicado: (2014)

Opposing Effects of Tcf3 and Tcf1 Control Wnt-Stimulation of Embryonic Stem Cell Self Renewal
por: Yi, Fei, et al.
Publicado: (2011)

Multiple Tumor Suppressor microRNAs Regulate Telomerase and TCF7, an Important Transcriptional Regulator of the Wnt Pathway
por: Hrdličková, Radmila, et al.
Publicado: (2014)

Evolutionary diversification of the canonical Wnt signaling effector TCF/LEF in chordates
por: Torres‐Aguila, Nuria P., et al.
Publicado: (2022)

Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4
por: Gallagher, Joseph M., et al.
Publicado: (2014)

SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells
por: Mukherjee, Shreyasi, et al.
Publicado: (2022)

Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling
por: Schepeler, Troels, et al.
Publicado: (2007)

Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity
por: He, Xiaoli, et al.
Publicado: (2017)

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency
por: Athanasouli, Paraskevi, et al.
Publicado: (2023)

GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos
por: Haworth, Kim E, et al.
Publicado: (2008)

Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression
por: Wallmen, Britta, et al.
Publicado: (2012)

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets
por: Weise, Andreas, et al.
Publicado: (2010)

Meta-connectomic analysis maps consistent, reproducible, and transcriptionally relevant functional connectome hubs in the human brain
por: Xu, Zhilei, et al.
Publicado: (2022)

The Transcription Factor TCF1 in T Cell Differentiation and Aging
por: Kim, Chulwoo, et al.
Publicado: (2020)

A Wnt-kinase network alters nuclear localization of TCF-1 in colon cancer
por: Najdi, Rani, et al.
Publicado: (2009)

Temporal Perturbation of the Wnt Signaling Pathway in the Control of Cell Reprogramming Is Modulated by TCF1
por: Aulicino, Francesco, et al.
Publicado: (2014)

Tcf7l2/Tcf4 Transcriptional Repressor Function Requires HDAC Activity in the Developing Vertebrate CNS
por: Wang, Hui, et al.
Publicado: (2016)

H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC
por: Carotenuto, Marianeve, et al.
Publicado: (2014)

Correction: Structure-Function Analysis of the C-clamp of TCF/Pangolin in Wnt/ß-catenin Signaling
Publicado: (2014)

Pja2 Inhibits Wnt/β-catenin Signaling by Reducing the Level of TCF/LEF1
por: Song, Yonghee, et al.
Publicado: (2018)

Role of TCF/LEF Transcription Factors in Bone Development and Osteogenesis
por: Li, Zhengqiang, et al.
Publicado: (2018)

TCF/LEF Transcription Factors: An Update from the Internet Resources
por: Hrckulak, Dusan, et al.
Publicado: (2016)

Narrowband UVB treatment induces expression of WNT7B, WNT10B and TCF7L2 in psoriasis skin
por: Assarsson, Malin, et al.
Publicado: (2019)

Bisected graph matching improves automated pairing of bilaterally homologous neurons from connectomes
por: Pedigo, Benjamin D., et al.
Publicado: (2023)

Distinct DNA Binding Sites Contribute to the TCF Transcriptional Switch in C. elegans and Drosophila
por: Bhambhani, Chandan, et al.
Publicado: (2014)

Wnt–β-catenin–Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer
por: Ravindranath, A, et al.
Publicado: (2011)

The TCF C-clamp DNA binding domain expands the Wnt transcriptome via alternative target recognition
por: Hoverter, Nate P., et al.
Publicado: (2014)

Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling
por: Han, Wonhee, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_j5s4hj0io6afshm01jm008vbm9