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Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo

BACKGROUND: Natural compounds have been demonstrated to lower breast cancer risk and sensitize tumor cells to anticancer therapies. Recently, we demonstrated that vernodalin (the active constituent of the medicinal herb Centratherum anthelminticum seeds) induces apoptosis in breast cancer cell-lines...

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Detalles Bibliográficos
Autores principales:	Ananda Sadagopan, Suresh Kumar, Mohebali, Nooshin, Looi, Chung Yeng, Hasanpourghadi, Mohadeseh, Pandurangan, Ashok Kumar, Arya, Aditya, Karimian, Hamed, Mustafa, Mohd Rais
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672543/ https://www.ncbi.nlm.nih.gov/pubmed/26643256 http://dx.doi.org/10.1186/s13046-015-0266-y

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