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Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding
BACKGROUND: Malaria is still one of the most prevalent infectious diseases in the world. Sequestration of infected erythrocytes (IEs) is the prime mediator of disease. Cytoadhesion of IEs is mediated by members of the highly diverse Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). A re...
Autores principales: | Nunes-Silva, Sofia, Dechavanne, Sébastien, Moussiliou, Azizath, Pstrąg, Natalia, Semblat, Jean-Philippe, Gangnard, Stéphane, Tuikue-Ndam, Nicaise, Deloron, Philippe, Chêne, Arnaud, Gamain, Benoît |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672576/ https://www.ncbi.nlm.nih.gov/pubmed/26646943 http://dx.doi.org/10.1186/s12936-015-1008-5 |
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