ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report

A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the...

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Detalles Bibliográficos
Autores principales: Takagi, Kimiaki, Takai, Manabu, Kameyama, Koji, Horie, Kengo, Kikuchi, Mina, Kato, Taku, Mizutani, Kosuke, Seike, Kensaku, Tsuchiya, Tomohiro, Yasuda, Mitsuru, Yokoi, Shigeaki, Suzui, Natsuko, Nakano, Masahiro, Deguchi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Inflammation and Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672650/
https://www.ncbi.nlm.nih.gov/pubmed/26793530
http://dx.doi.org/10.1016/j.eucr.2015.06.003
Descripción
Sumario:A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).

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