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ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report

A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the...

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Autores principales: Takagi, Kimiaki, Takai, Manabu, Kameyama, Koji, Horie, Kengo, Kikuchi, Mina, Kato, Taku, Mizutani, Kosuke, Seike, Kensaku, Tsuchiya, Tomohiro, Yasuda, Mitsuru, Yokoi, Shigeaki, Suzui, Natsuko, Nakano, Masahiro, Deguchi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672650/
https://www.ncbi.nlm.nih.gov/pubmed/26793530
http://dx.doi.org/10.1016/j.eucr.2015.06.003
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author Takagi, Kimiaki
Takai, Manabu
Kameyama, Koji
Horie, Kengo
Kikuchi, Mina
Kato, Taku
Mizutani, Kosuke
Seike, Kensaku
Tsuchiya, Tomohiro
Yasuda, Mitsuru
Yokoi, Shigeaki
Suzui, Natsuko
Nakano, Masahiro
Deguchi, Takashi
author_facet Takagi, Kimiaki
Takai, Manabu
Kameyama, Koji
Horie, Kengo
Kikuchi, Mina
Kato, Taku
Mizutani, Kosuke
Seike, Kensaku
Tsuchiya, Tomohiro
Yasuda, Mitsuru
Yokoi, Shigeaki
Suzui, Natsuko
Nakano, Masahiro
Deguchi, Takashi
author_sort Takagi, Kimiaki
collection PubMed
description A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).
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spelling pubmed-46726502016-01-20 ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report Takagi, Kimiaki Takai, Manabu Kameyama, Koji Horie, Kengo Kikuchi, Mina Kato, Taku Mizutani, Kosuke Seike, Kensaku Tsuchiya, Tomohiro Yasuda, Mitsuru Yokoi, Shigeaki Suzui, Natsuko Nakano, Masahiro Deguchi, Takashi Urol Case Rep Inflammation and Infection A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK). Elsevier 2015-07-02 /pmc/articles/PMC4672650/ /pubmed/26793530 http://dx.doi.org/10.1016/j.eucr.2015.06.003 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Inflammation and Infection
Takagi, Kimiaki
Takai, Manabu
Kameyama, Koji
Horie, Kengo
Kikuchi, Mina
Kato, Taku
Mizutani, Kosuke
Seike, Kensaku
Tsuchiya, Tomohiro
Yasuda, Mitsuru
Yokoi, Shigeaki
Suzui, Natsuko
Nakano, Masahiro
Deguchi, Takashi
ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report
title ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report
title_full ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report
title_fullStr ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report
title_full_unstemmed ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report
title_short ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report
title_sort alk gene translocation in inflammatory myofibroblastic tumor of the urinary bladder: a case report
topic Inflammation and Infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672650/
https://www.ncbi.nlm.nih.gov/pubmed/26793530
http://dx.doi.org/10.1016/j.eucr.2015.06.003
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