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C/EBPβ-LAP*/LAP Expression Is Mediated by RSK/eIF4B-Dependent Signalling and Boosted by Increased Protein Stability in Models of Monocytic Differentiation
The transcription factor C/EBPβ plays a key role in monocytic differentiation and inflammation. Its small isoform LIP is associated with proliferation at early premonocytic developmental stages and regulated via mTOR-dependent signalling. During later stages of (pre)monocytic differentiation there i...
Autores principales: | Huber, René, Panterodt, Thomas, Welz, Bastian, Christmann, Martin, Friesenhagen, Judith, Westphal, Andreas, Pietsch, Daniel, Brand, Korbinian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672875/ https://www.ncbi.nlm.nih.gov/pubmed/26646662 http://dx.doi.org/10.1371/journal.pone.0144338 |
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