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Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

Human β-defensin 3 (hBD3) is a cationic host defence peptide and is part of the innate immune response. HBD3 is present on a highly copy number variable block of six β-defensin genes, and increased copy number is associated with the autoimmune disease psoriasis. It is not known how this increase inf...

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Detalles Bibliográficos
Autores principales:	Semple, Fiona, MacPherson, Heather, Webb, Sheila, Kilanowski, Fiona, Lettice, Laura, McGlasson, Sarah L., Wheeler, Ann P., Chen, Valerie, Millhauser, Glenn L., Melrose, Lauren, Davidson, Donald J., Dorin, Julia R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672878/ https://www.ncbi.nlm.nih.gov/pubmed/26646717 http://dx.doi.org/10.1371/journal.pgen.1005673

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