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Disruption of Specific RNA-RNA Interactions in a Double-Stranded RNA Virus Inhibits Genome Packaging and Virus Infectivity

Bluetongue virus (BTV) causes hemorrhagic disease in economically important livestock. The BTV genome is organized into ten discrete double-stranded RNA molecules (S1-S10) which have been suggested to follow a sequential packaging pathway from smallest to largest segment during virus capsid assembly...

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Detalles Bibliográficos
Autores principales:	Fajardo, Teodoro, Sung, Po-Yu, Roy, Polly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672896/ https://www.ncbi.nlm.nih.gov/pubmed/26646790 http://dx.doi.org/10.1371/journal.ppat.1005321

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