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Transcriptome-Wide Cleavage Site Mapping on Cellular mRNAs Reveals Features Underlying Sequence-Specific Cleavage by the Viral Ribonuclease SOX

Many viruses express factors that reduce host gene expression through widespread degradation of cellular mRNA. An example of this class of proteins is the mRNA-targeting endoribonuclease SOX from the gamma-herpesvirus Kaposi’s sarcoma-associated herpesvirus (KSHV). Previous studies indicated that cl...

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Detalles Bibliográficos
Autores principales: Gaglia, Marta Maria, Rycroft, Chris H., Glaunsinger, Britt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672902/
https://www.ncbi.nlm.nih.gov/pubmed/26646420
http://dx.doi.org/10.1371/journal.ppat.1005305