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Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma
Prognosis remains extremely poor for malignant glioma. Targeted therapeutic approaches, including single agent anti-angiogenic and proteasome inhibition strategies, have not resulted in sustained anti-glioma clinical efficacy. We tested the anti-glioma efficacy of the anti-angiogenic receptor tyrosi...
Autores principales: | Lobo, Merryl R., Kukino, Ayaka, Tran, Huong, Schabel, Matthias C., Springer, Charles S., Gillespie, G. Yancey, Grafe, Marjorie R., Woltjer, Randall L., Pike, Martin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672903/ https://www.ncbi.nlm.nih.gov/pubmed/26645398 http://dx.doi.org/10.1371/journal.pone.0144488 |
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