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Probing Xist RNA Structure in Cells Using Targeted Structure-Seq

The long non-coding RNA (lncRNA) Xist is a master regulator of X-chromosome inactivation in mammalian cells. Models for how Xist and other lncRNAs function depend on thermodynamically stable secondary and higher-order structures that RNAs can form in the context of a cell. Probing accessible RNA bas...

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Detalles Bibliográficos
Autores principales:	Fang, Rui, Moss, Walter N., Rutenberg-Schoenberg, Michael, Simon, Matthew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672913/ https://www.ncbi.nlm.nih.gov/pubmed/26646615 http://dx.doi.org/10.1371/journal.pgen.1005668

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