Cargando…
GADD45a physically and functionally interacts with TET1
DNA demethylation plays a central role during development and in adult physiology. Different mechanisms of active DNA demethylation have been established. For example, Growth Arrest and DNA Damage 45-(GADD45) and Ten-Eleven-Translocation (TET) proteins act in active DNA demethylation but their funct...
Autores principales: | Kienhöfer, Sabine, Musheev, Michael U., Stapf, Ulrike, Helm, Mark, Schomacher, Lars, Niehrs, Christof, Schäfer, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673086/ https://www.ncbi.nlm.nih.gov/pubmed/26546041 http://dx.doi.org/10.1016/j.diff.2015.10.003 |
Ejemplares similares
-
GADD45A binds R-loops and recruits TET1 to CpG island promoters
por: Arab, Khelifa, et al.
Publicado: (2019) -
Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation
por: Schomacher, Lars, et al.
Publicado: (2016) -
GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells
por: Schüle, Katrin M., et al.
Publicado: (2019) -
Gadd45a Is an RNA Binding Protein and Is Localized in Nuclear Speckles
por: Sytnikova, Yuliya A., et al.
Publicado: (2011) -
Mammalian N1-adenosine PARylation is a reversible DNA modification
por: Musheev, Michael U., et al.
Publicado: (2022)