Cargando…

Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer

Large cell carcinoma with or without neuroendocrine features (LCNEC and LC, respectively) constitutes 3–9% of non-small cell lung cancer but is poorly characterized at the molecular level. Herein we analyzed 41 LC and 32 LCNEC (including 15 previously reported cases) tumors using massive parallel se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karlsson, Anna, Brunnström, Hans, Lindquist, Kajsa Ericson, Jirström, Karin, Jönsson, Mats, Rosengren, Frida, Reuterswärd, Christel, Cirenajwis, Helena, Borg, Åke, Jönsson, Per, Planck, Maria, Jönsson, Göran, Staaf, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673143/ https://www.ncbi.nlm.nih.gov/pubmed/26124082

Ejemplares similares

Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer
por: Lindquist, Kajsa Ericson, et al.
Publicado: (2017)

Clinical Utility of Targeted Sequencing in Lung Cancer: Experience From an Autonomous Swedish Health Care Center
por: Isaksson, Sofi, et al.
Publicado: (2020)

A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer
por: Karlsson, Anna, et al.
Publicado: (2019)

Targeted sequencing may facilitate differential diagnostics of pulmonary tumours: a case series
por: Ericson-Lindquist, Kajsa, et al.
Publicado: (2017)

CA 19-9 and CA 125 as potential predictors of disease recurrence in resectable lung adenocarcinoma
por: Isaksson, Sofi, et al.
Publicado: (2017)

Relation between smoking history and gene expression profiles in lung adenocarcinomas
por: Staaf, Johan, et al.
Publicado: (2012)

Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours
por: Howlin, Jillian, et al.
Publicado: (2015)

Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non‐small cell lung cancer
por: Salomonsson, Annette, et al.
Publicado: (2020)

Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer
por: Staaf, Johan, et al.
Publicado: (2011)

Methylation Patterns and Chromatin Accessibility in Neuroendocrine Lung Cancer
por: Arbajian, Elsa, et al.
Publicado: (2020)

Performance of gene expression–based single sample predictors for assessment of clinicopathological subgroups and molecular subtypes in cancers: a case comparison study in non-small cell lung cancer
por: Cirenajwis, Helena, et al.
Publicado: (2019)

Molecular stratification of metastatic melanoma using gene expression profiling : Prediction of survival outcome and benefit from molecular targeted therapy
por: Cirenajwis, Helena, et al.
Publicado: (2015)

Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
por: Holm, Karolina, et al.
Publicado: (2010)

PD-L1 Expression in Non-Small Cell Lung Cancer Specimens: Association with Clinicopathological Factors and Molecular Alterations
por: Mansour, Mohammed S. I., et al.
Publicado: (2022)

Feasibility of EBUS-TBNA for histopathological and molecular diagnostics of NSCLC—A retrospective single-center experience
por: Karadzovska-Kotevska, Marija, et al.
Publicado: (2022)

Tumor Genome Wide DNA Alterations Assessed by Array CGH in Patients with Poor and Excellent Survival Following Operation for Colorectal Cancer
por: Lagerstedt, Kristina K., et al.
Publicado: (2007)

Normalization of array-CGH data: influence of copy number imbalances
por: Staaf, Johan, et al.
Publicado: (2007)

Associations of beta-catenin alterations and MSI screening status with expression of key cell cycle regulating proteins and survival from colorectal cancer
por: Wangefjord, Sakarias, et al.
Publicado: (2013)

DNA methylation subgroups in melanoma are associated with proliferative and immunological processes
por: Lauss, Martin, et al.
Publicado: (2015)

Large TPC infrastructure
por: Colas, P., et al.
Publicado: (2014)

An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells
por: Holm, Karolina, et al.
Publicado: (2016)

NF1‐mutated melanoma tumors harbor distinct clinical and biological characteristics
por: Cirenajwis, Helena, et al.
Publicado: (2017)

Molecular and genetic diversity in the metastatic process of melanoma
por: Harbst, Katja, et al.
Publicado: (2014)

Multiple drivers of large‐scale lichen decline in boreal forest canopies
por: Esseen, Per‐Anders, et al.
Publicado: (2022)

Dimensions and Interactions of Large T-Cell Surface Proteins
por: Junghans, Victoria, et al.
Publicado: (2018)

Core Outcome Sets (COS) related to pregnancy and childbirth: a systematic review
por: Österberg, Marie, et al.
Publicado: (2021)

Mutational Landscape in Resected Periampullary Adenocarcinoma: Relationship With Morphology and Clinical Outcome
por: Lundgren, Sebastian, et al.
Publicado: (2019)

A gene expression‐based single sample predictor of lung adenocarcinoma molecular subtype and prognosis
por: Liljedahl, Helena, et al.
Publicado: (2020)

High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer
por: Staaf, Johan, et al.
Publicado: (2010)

Mycoplasma pneumonia with severe cold agglutinin hemolysis, thrombocytosis, leukemoid reaction and acute renal failure
por: Widén, Johan, et al.
Publicado: (2023)

Intronic and plasmid-derived regions contribute to the large mitochondrial genome sizes of Agaricomycetes
por: Himmelstrand, Kajsa, et al.
Publicado: (2014)

Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer
por: Micke, Patrick, et al.
Publicado: (2019)

Distinct Gene Expression Signatures in Lynch Syndrome and Familial Colorectal Cancer Type X
por: Dominguez-Valentin, Mev, et al.
Publicado: (2013)

Pulmonary large cell carcinoma with neuroendocrine morphology shows genetic similarity to large cell neuroendocrine carcinoma
por: Liang, Zuoyu, et al.
Publicado: (2022)

Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study
por: Wangefjord, Sakarias, et al.
Publicado: (2013)

Large-cell neuroendocrine carcinoma of the cervix
por: Yoseph, Benyam, et al.
Publicado: (2012)

Management of Large Cell Neuroendocrine Carcinoma
por: Corbett, Virginia, et al.
Publicado: (2021)

Pulmonary Large Cell Neuroendocrine Carcinoma
por: Yang, Lan, et al.
Publicado: (2022)

Pharmacometrics-Based Considerations for the Design of a Pharmacogenomic Clinical Trial Assessing Irinotecan Safety
por: Minichmayr, Iris K., et al.
Publicado: (2021)

Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer
por: Larsson, Anna, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_t6miri3bgbcgkl4orja73ieso5