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Functional relevance of a six mesenchymal gene signature in epithelial-mesenchymal transition (EMT) reversal by the triple angiokinase inhibitor, nintedanib (BIBF1120)
Epithelial-mesenchymal transition (EMT), a crucial mechanism in carcinoma progression, describes the process whereby epithelial cells lose their apico-basal polarity and junctional complexes and acquire a mesenchymal-like morphology. Several markers are considered to be authentic indicators of an ep...
Autores principales: | Huang, Ruby Yun-Ju, Kuay, Kuee Theng, Tan, Tuan Zea, Asad, Mohammad, Tang, Hei Mui, Ng, Aloysius Hsien Chun, Ye, Jieru, Chung, Vin Yee, Thiery, Jean Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673149/ https://www.ncbi.nlm.nih.gov/pubmed/26061747 |
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