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Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth

Naked cuticle homolog 2 (NKD2) has been reported to antagonize Wnt signaling in zebrafish, mouse and mammals. The aim of this study is to investigate the epigenetic changes and mechanisms of NKD2 in human breast cancer development. Six breast cancer cell lines (MCF-7, ZR75-1, MDA-MB-468, MDA-MB-231,...

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Detalles Bibliográficos
Autores principales:	Dong, Yan, Cao, Baoping, Zhang, Meiying, Han, Weidong, Herman, James G., Fuks, François, Zhao, Yali, Guo, Mingzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673151/ https://www.ncbi.nlm.nih.gov/pubmed/26124080

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