Cargando…

Upfront molecular testing in patients with advanced gastro-esophageal cancer: Is it time yet?

INTRODUCTION: Targeting HER2 has improved outcomes in metastatic GE (mGE) cancer. In this study, we aim to explore the feasibility of molecular profiling in patients with refractory mGE cancer in routine clinical practice. METHODS: Archival formalin-fixed, paraffin-embedded (FFPE) samples for patien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mikhail, Sameh, Ciombor, Kristen, Noonan, Anne, Wu, Christina, Goldberg, Richard, Zhao, Weiqiang, Wei, Lai, Mathey, Kristina, Yereb, Melissa, Timmers, Cynthia, Bekaii-Saab, Tanios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673157/ https://www.ncbi.nlm.nih.gov/pubmed/26082439

Ejemplares similares

Immunological predictors of overall survival in treatment naïve metastatic pancreatic cancer patients
por: Farren, Matthew R, et al.
Publicado: (2015)

Whole-exome tumor sequencing study in biliary cancer patients with a response to MEK inhibitors
por: Ahn, Daniel H., et al.
Publicado: (2015)

New developments in the treatment of metastatic gastric cancer: focus on trastuzumab
por: Rose, Jeffrey S, et al.
Publicado: (2011)

CpG Island Methylation, Microsatellite Instability, and BRAF Mutations and Their Clinical Application in the Treatment of Colon Cancer
por: Wu, Christina, et al.
Publicado: (2012)

Update to “Homologous Recombination Repair Defect May Predict Treatment Response to Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors”
por: Zhu, Mojun, et al.
Publicado: (2022)

Management of Venous Thromboembolism in Patients with Advanced Gastrointestinal Cancers: What Is the Role of Novel Oral Anticoagulants?
por: Martin, Ludmila Katherine, et al.
Publicado: (2012)

The Continued Promise and Many Disappointments of Oncolytic Virotherapy in Gastrointestinal Malignancies
por: Ahn, Daniel H., et al.
Publicado: (2017)

Response to Drs Von Hoff and Renschler
por: Ahn, Daniel H., et al.
Publicado: (2017)

Identifying and targeting cancer stem cells in the treatment of gastric cancer
por: Bekaii‐Saab, Tanios, et al.
Publicado: (2017)

Pemigatinib for adults with previously treated, locally advanced or metastatic cholangiocarcinoma with FGFR2 fusions/rearrangements
por: Walden, Daniel, et al.
Publicado: (2022)

A phase II and pharmacodynamic study of sunitinib in relapsed/refractory oesophageal and gastro-oesophageal cancers
por: Wu, C, et al.
Publicado: (2015)

Spotlight on bevacizumab in metastatic colorectal cancer: patient selection and perspectives
por: Bupathi, Manojkumar, et al.
Publicado: (2016)

Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC)
por: Overholser, Jay, et al.
Publicado: (2015)

Emerging Therapies and Future Directions in Targeting the Tumor Stroma and Immune System in the Treatment of Pancreatic Adenocarcinoma
por: Ahn, Daniel H., et al.
Publicado: (2018)

Therapeutic Targeting Strategies of Cancer Stem Cells in Gastrointestinal Malignancies
por: Sonbol, Mohamad B., et al.
Publicado: (2019)

Frontline therapy for advanced hepatocellular carcinoma: an update
por: Akce, Mehmet, et al.
Publicado: (2022)

Complete clinical response of metastatic hepatocellular carcinoma to sorafenib in a patient with hemochromatosis: A case report
por: So, Brian J, et al.
Publicado: (2008)

Gastro-Esophageal Reflux in Children
por: Rybak, Anna, et al.
Publicado: (2017)

A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma
por: Bekaii-Saab, Tanios, et al.
Publicado: (2006)

Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model
por: Kaumaya, Pravin T. P., et al.
Publicado: (2020)

Postoperative Radiotherapy for Thoracic Esophageal Carcinoma with Upfront R0 Esophagectomy
por: Wang, Yichun, et al.
Publicado: (2020)

Adjuvant therapy for pancreas cancer in an era of value based cancer care
por: Ahn, Daniel H., et al.
Publicado: (2015)

Two Cases of Esophageal Eosinophilia: Eosinophilic Esophagitis or Gastro-Esophageal Reflux Disease?
por: Yilmaz, Ozlem, et al.
Publicado: (2014)

INTEGRATE II: randomised phase III controlled trials of regorafenib containing regimens versus standard of care in refractory Advanced Gastro-Oesophageal Cancer (AGOC): a study by the Australasian Gastro-Intestinal Trials Group (AGITG)
por: Lam, Lyn Ley, et al.
Publicado: (2023)

Endoscopic evaluation of gastro-esophageal reflux disease.
por: Armstrong, D.
Publicado: (1999)

Evaluation of frozen tissue-derived prognostic gene expression signatures in FFPE colorectal cancer samples
por: Zhu, Jing, et al.
Publicado: (2016)

Invasive Treatment Options for Gastro-Esophageal Reflux Disease
por: Dumitru, Vlad, et al.
Publicado: (2020)

Significance of Non-erosive Minimal Esophageal Lesions in Gastro-esophageal Reflux Disorder
por: Hong, Sung-Pyo, et al.
Publicado: (2004)

Mechanism of spirometry associated gastro-esophageal reflux in individuals undergoing esophageal assessment
por: Xu, Matthew, et al.
Publicado: (2023)

Preschool Wheezing and Gastro-Esophageal Reflux: --Causal or Casual Coincidence? Update from Literature
por: Borrelli, Melissa, et al.
Publicado: (2021)

The association between reflux esophagitis and airway hyper-reactivity in patients with gastro-esophageal reflux
por: Karbasi, Ashraf, et al.
Publicado: (2013)

Phase I trial of hypofractionated chemoradiotherapy in the palliative management of esophageal and gastro-esophageal cancer
por: Sridharan, Swetha, et al.
Publicado: (2022)

The potential therapeutic effect of melatonin in gastro-esophageal reflux disease
por: Kandil, Tharwat S, et al.
Publicado: (2010)

Gastro-Esophageal Reflux Disease in Healthy Older Children and Adolescents
por: Park, Kie Young, et al.
Publicado: (2012)

Diagnostic Criteria for Gastro-esophageal Reflux Following Sleeve Gastrectomy
por: Lim, Gillian, et al.
Publicado: (2021)

Spontaneous Regression of Metastatic Lesions of Adenocarcinoma of the Gastro-Esophageal Junction
por: Mitchell, Richard, et al.
Publicado: (2021)

Gastro-Esophageal Reflux Disease and Paroxysmal Atrial Fibrillation Ablation
por: Floria, Mariana, et al.
Publicado: (2023)

Using Naïve Bayesian Analysis to Determine Imaging Characteristics of KRAS Mutations in Metastatic Colon Cancer
por: Pershad, Yash, et al.
Publicado: (2017)

Impact of Tumor Location and Variables Associated With Overall Survival in Patients With Colorectal Cancer: A Mayo Clinic Colon and Rectal Cancer Registry Study
por: Wang, Cassia B., et al.
Publicado: (2019)

Maintenance Therapy in First-Line Gastric and Gastroesophageal Junction Adenocarcinoma: A Retrospective Analysis
por: Walden, Daniel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6vihe20cqnn4sfu42mcl84crcj