AS1411-conjugated gold nanospheres and their potential for breast cancer therapy

AS1411 is a quadruplex-forming DNA oligonucleotide that functions as an aptamer to target nucleolin, a protein present on the surface of cancer cells. Clinical trials of AS1411 have indicated it is well tolerated with evidence of therapeutic activity, but improved pharmacology and potency may be req...

Descripción completa

Detalles Bibliográficos
Autores principales: Malik, Mohammad T., O'Toole, Martin G., Casson, Lavona K., Thomas, Shelia D., Bardi, Gina T., Reyes-Reyes, Elsa Merit, Ng, Chin K., Kang, Kyung A., Bates, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673162/
https://www.ncbi.nlm.nih.gov/pubmed/26045302

Ejemplares similares

Ejemplares similares