Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells

Multidrug resistance has appeared to mitigate the efficiency of anticancer drugs and the possibility of successful cancer chemotherapy. The Hedgehog receptor Patched is a multidrug transporter expressed in several cancers and as such it represents a new target to circumvent chemotherapy resistance....

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Detalles Bibliográficos
Autores principales: Fiorini, Laura, Tribalat, Marie-Aude, Sauvard, Lucy, Cazareth, Julie, Lalli, Enzo, Broutin, Isabelle, Thomas, Olivier P., Mus-Veteau, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673163/
https://www.ncbi.nlm.nih.gov/pubmed/26068979

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