CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells

NANOG expression in prostate cancer is highly correlated with cancer stem cell characteristics and resistance to androgen deprivation. However, it is not clear whether NANOG or its pseudogenes contribute to the malignant potential of cancer. We established NANOG- and NANOGP8-knockout DU145 prostate...

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Detalles Bibliográficos
Autores principales: Kawamura, Norihiko, Nimura, Keisuke, Nagano, Hiromichi, Yamaguchi, Sohei, Nonomura, Norio, Kaneda, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673169/
https://www.ncbi.nlm.nih.gov/pubmed/26087476

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