Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition

Glioblastoma are among the most angiogenic tumors. The molecular mechanisms that control blood vessel formation by endothelial cells (EC) in glioblastoma remain incompletely understood. Transforming growth factor-β (TGF-β) is a key regulatory cytokine that has proinvasive and stemness-maintaining au...

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Detalles Bibliográficos
Autores principales: Krishnan, Shanmugarajan, Szabo, Emese, Burghardt, Isabel, Frei, Karl, Tabatabai, Ghazaleh, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673177/
https://www.ncbi.nlm.nih.gov/pubmed/26090865

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