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Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis
Translocation of the pro-apoptotic protein Bax from the cytosol to the mitochondria is a crucial step in DNA damage-mediated apoptosis, and is also found to be involved in mitochondrial fragmentation. Irradiation-induced cytochrome c release and apoptosis was associated with Bax activation, but not...
Autores principales: | Wang, Ping, Wang, Peiguo, Liu, Becky, Zhao, Jing, Pang, Qingsong, Agrawal, Samir G., Jia, Li, Liu, Feng-Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673185/ https://www.ncbi.nlm.nih.gov/pubmed/26093086 |
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