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Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis

Translocation of the pro-apoptotic protein Bax from the cytosol to the mitochondria is a crucial step in DNA damage-mediated apoptosis, and is also found to be involved in mitochondrial fragmentation. Irradiation-induced cytochrome c release and apoptosis was associated with Bax activation, but not...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Wang, Peiguo, Liu, Becky, Zhao, Jing, Pang, Qingsong, Agrawal, Samir G., Jia, Li, Liu, Feng-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673185/
https://www.ncbi.nlm.nih.gov/pubmed/26093086

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