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RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop
Glioblastomas (GBMs), the most aggressive primary brain tumors, exhibit increased invasiveness and resistance to anti-tumor treatments. We explored the role of RTVP-1, a glioma-associated protein that promotes glioma cell migration, in the mesenchymal transformation of GBM. Analysis of The Cancer Ge...
Autores principales: | Giladi, Nis David, Ziv-Av, Amotz, Lee, Hae Kyung, Finniss, Susan, Cazacu, Simona, Xiang, Cunli, Ben-Asher, Hiba Waldman, deCarvalho, Ana, Mikkelsen, Tom, Poisson, Laila, Brodie, Chaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673191/ https://www.ncbi.nlm.nih.gov/pubmed/26267319 |
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