Epigenetic inactivation of the candidate tumor suppressor gene ASC/TMS1 in human renal cell carcinoma and its role as a potential therapeutic target

This study investigated the epigenetic alteration and biological function of the pro-apoptotic gene ASC/TMS1 in renal cell carcinoma. ASC/TMS1 was downregulated in five out of six RCC cell lines. A significant downregulation was also detected in sixty-seven paired renal tumors compared with adjacent...

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Detalles Bibliográficos
Autores principales: Liu, Qianling, Jin, Jie, Ying, Jianming, Cui, Yun, Sun, Mengkui, Zhang, Lian, Fan, Yu, Xu, Ben, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673193/
https://www.ncbi.nlm.nih.gov/pubmed/26093088

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