Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation

Hypoxia is an independent prognostic indicator of poor outcome in several malignancies. However, precise mechanism through which hypoxia promotes disease aggressiveness is still unclear. Here, we report that under hypoxia (1% O(2)), human prostate cancer (PCA) cells, and extracellular vesicles (EVs)...

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Detalles Bibliográficos
Autores principales: Schlaepfer, Isabel R., Nambiar, Dhanya K., Ramteke, Anand, Kumar, Rahul, Dhar, Deepanshi, Agarwal, Chapla, Bergman, Bryan, Graner, Michael, Maroni, Paul, Singh, Rana P., Agarwal, Rajesh, Deep, Gagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673203/
https://www.ncbi.nlm.nih.gov/pubmed/26087400

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