Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression

CCNE1 gene amplification is present in 15-20% ovary tumor specimens. Here, we showed that Cyclin E1 (CCNE1) was overexpressed in 30% of established ovarian cancer cell lines. We also showed that CCNE1 was stained positive in over 40% of primary ovary tumor specimens regardless of their histological...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Fang, Dongdong, Chen, Huijun, Lu, Yiyu, Dong, Zheng, Ding, Han-Fei, Jing, Qing, Su, Shi-Bing, Huang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673230/
https://www.ncbi.nlm.nih.gov/pubmed/26204491

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