Cargando…

The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis

The TRAF-interacting protein (TRAIP) is an E3 ubiquitin ligase required for cell proliferation. TRAIP mRNA is downregulated in human keratinocytes after inhibition of the PI3K/AKT/mTOR signaling. Since E2F transcription factors are downstream of PI3K/AKT/mTOR we investigated whether they regulate TR...

Descripción completa

Detalles Bibliográficos
Autores principales: Chapard, Christophe, Hohl, Daniel, Huber, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673240/
https://www.ncbi.nlm.nih.gov/pubmed/26369285